{"id":7513,"date":"2018-06-18T14:37:57","date_gmt":"2018-06-18T13:37:57","guid":{"rendered":"http:\/\/histoweb.com\/?p=7513"},"modified":"2022-11-14T18:55:06","modified_gmt":"2022-11-14T17:55:06","slug":"melanoma","status":"publish","type":"post","link":"https:\/\/histoweb.com\/en\/melanoma\/","title":{"rendered":"Melanoma"},"content":{"rendered":"

In humans, melanomas are one of the most frequent and aggressive neoplasms and, although the incidence of skin forms has variability depending on the geographic area, uveal and mucocutaneous melanomas have a homogeneous morbidity. Both,\u00a0in the case of skin melanomas related to UV radiation and in mucocutaneous tumors genetic abnormalities have been identified. Spontaneous melanomas in dogs are a model of their counterparts in the human species based on their inter-individual and intratumoral heterogeneity, metastasis, relapses and resistance to treatment. In this review work, authors carry out a comparative study of cutaneous and mucocutaneous melanomas in humans and dogs, reviewing clinical manifestations, genetic bases and different therapeutic alternatives.<\/p>\n

Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas. Int J Mol Sci. 2018 Jan 30;19(2).<\/a><\/p>\n

Archive<\/p>\n

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In humans, melanomas are one of the most frequent and aggressive neoplasms and, although the incidence of skin forms has variability depending on the geographic area, uveal and mucocutaneous melanomas have a homogeneous morbidity. Both,\u00a0in the case of skin melanomas related to UV radiation and in mucocutaneous tumors genetic abnormalities have been identified. Spontaneous melanomas […]<\/p>\n","protected":false},"author":2,"featured_media":7413,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-7513","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-web-journal-en"],"yoast_head":"\nMelanoma - Histoweb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/histoweb.com\/en\/melanoma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melanoma - Histoweb\" \/>\n<meta property=\"og:description\" content=\"In humans, melanomas are one of the most frequent and aggressive neoplasms and, although the incidence of skin forms has variability depending on the geographic area, uveal and mucocutaneous melanomas have a homogeneous morbidity. 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