{"id":6432,"date":"2016-01-16T18:23:35","date_gmt":"2016-01-16T17:23:35","guid":{"rendered":"http:\/\/histoweb.com\/pt-pt\/?p=6432"},"modified":"2022-11-14T19:03:00","modified_gmt":"2022-11-14T18:03:00","slug":"the-worm-turns","status":"publish","type":"post","link":"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/","title":{"rendered":"The worm turns"},"content":{"rendered":"<p>A co-infe\u00e7\u00e3o em ratinhos com Schistosoma mansoni reduz a mortalidade induzida por Toxocara canis e previne as les\u00f5es cerebrais relacionadas a Plasmodium e, pelo contr\u00e1rio, promove a replica\u00e7\u00e3o de Leishmania e aumenta a susceptibilidade \u00e0 tuberculose. Estas intera\u00e7\u00f5es s\u00e3o dif\u00edceis de compreender baixo o enfoque reducionista dos &#8220;postulados de Koch&#8221;, que se forjaram para determinar quando um organismo podia ser considerado respons\u00e1vel da uma doen\u00e7a. O resultado da infec\u00e7\u00e3o com um organismo determinado n\u00e3o sempre equivale \u00e0 doen\u00e7a. Al\u00e9m dos antecedentes gen\u00e9ticos, a interse\u00e7\u00e3o das influ\u00eancias dos organismos que co-infectam (desde a microflora simbi\u00f3tica aos patog\u00e9nicos virulentos) influem no resultado da infec\u00e7\u00e3o. E, devido a sua capacidade para conduzir a imunoregula\u00e7\u00e3o do h\u00f3spede e as infec\u00e7\u00f5es cr\u00f3nicas, os helmintes proporcionam exemplos do potencial das co-infec\u00e7\u00f5es em alterar o diagn\u00f3stico, o curso e o resultado dos processos de doen\u00e7a. Este articulo descreve como as infec\u00e7\u00f5es por helmintes imunoregulam a resposta inflamat\u00f3ria e as rea\u00e7\u00f5es autoimunes, e como modulam a patogenicidade, o curso e o resultado \u00e0 infec\u00e7\u00e3o concorrente com outros agentes patog\u00e9nicos.<\/p>\n<p><a href=\"http:\/\/vet.sagepub.com\/content\/51\/2\/385.full.pdf\">The Worm Turns: Trematodes Steering the Course of Co-infections. <\/a>Vet Pathol 2014 51:328-340<\/p>\n<p style=\"text-align: center;\">Archivo<\/p>\n<p><a href=\"\/pt-pt\/web-journal\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-4197 size-medium\" src=\"https:\/\/histoweb.com\/wp-content\/uploads\/2014\/11\/logo-web-journal-300x62.jpg\" alt=\"logo web journal\" width=\"300\" height=\"62\" srcset=\"https:\/\/histoweb.com\/wp-content\/uploads\/2014\/11\/logo-web-journal-300x62.jpg 300w, https:\/\/histoweb.com\/wp-content\/uploads\/2014\/11\/logo-web-journal.jpg 600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A co-infe\u00e7\u00e3o em ratinhos com Schistosoma mansoni reduz a mortalidade induzida por Toxocara canis e previne as les\u00f5es cerebrais relacionadas a Plasmodium e, pelo contr\u00e1rio, promove a replica\u00e7\u00e3o de Leishmania e aumenta a susceptibilidade \u00e0 tuberculose. Estas intera\u00e7\u00f5es s\u00e3o dif\u00edceis de compreender baixo o enfoque reducionista dos &#8220;postulados de Koch&#8221;, que se forjaram para determinar [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":6425,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-6432","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-web-journal-pt"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The worm turns - Histoweb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The worm turns - Histoweb\" \/>\n<meta property=\"og:description\" content=\"A co-infe\u00e7\u00e3o em ratinhos com Schistosoma mansoni reduz a mortalidade induzida por Toxocara canis e previne as les\u00f5es cerebrais relacionadas a Plasmodium e, pelo contr\u00e1rio, promove a replica\u00e7\u00e3o de Leishmania e aumenta a susceptibilidade \u00e0 tuberculose. Estas intera\u00e7\u00f5es s\u00e3o dif\u00edceis de compreender baixo o enfoque reducionista dos &#8220;postulados de Koch&#8221;, que se forjaram para determinar [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/\" \/>\n<meta property=\"og:site_name\" content=\"Histoweb\" \/>\n<meta property=\"article:published_time\" content=\"2016-01-16T17:23:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-14T18:03:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/histoweb.com\/wp-content\/uploads\/2016\/01\/Robert_Koch_BeW2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"225\" \/>\n\t<meta property=\"og:image:height\" content=\"225\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Histovet\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Histovet\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo estimado de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/\"},\"author\":{\"name\":\"Histovet\",\"@id\":\"https:\/\/histoweb.com\/#\/schema\/person\/d78fc7be2f2d4a1a7ddbe14459fec354\"},\"headline\":\"The worm turns\",\"datePublished\":\"2016-01-16T17:23:35+00:00\",\"dateModified\":\"2022-11-14T18:03:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/\"},\"wordCount\":216,\"publisher\":{\"@id\":\"https:\/\/histoweb.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/histoweb.com\/wp-content\/uploads\/2016\/01\/Robert_Koch_BeW2.jpg\",\"articleSection\":[\"Artigos\"],\"inLanguage\":\"pt-PT\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/\",\"url\":\"https:\/\/histoweb.com\/pt-pt\/the-worm-turns\/\",\"name\":\"The worm turns - 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