{"id":7520,"date":"2018-06-18T14:37:57","date_gmt":"2018-06-18T13:37:57","guid":{"rendered":"http:\/\/histoweb.com\/?p=7520"},"modified":"2022-11-14T19:02:20","modified_gmt":"2022-11-14T18:02:20","slug":"melanoma","status":"publish","type":"post","link":"https:\/\/histoweb.com\/pt-pt\/melanoma\/","title":{"rendered":"Melanoma"},"content":{"rendered":"<p>Nos seres humanos, os melanomas s\u00e3o uma das neoplasias mais agressivas que, se a incid\u00eancia de formas cut\u00e2neas apresenta variabilidade dependendo da \u00e1rea geogr\u00e1fica, os melanomas \u00favidos e mucocutanos apresentam morbidades homog\u00eaneas. Tant na melanomes melanomes cutanis relaciona-se com a radia\u00e7\u00e3o UV em els mucocutanis s&#8217;han identifica diversas anomalias gen\u00e9ticas. O melanos spontanis em gossos \u00e9 um modelo do hom\u00f3logo da esp\u00e9cie humana baseado na heterogeneidade interindividual e intratumoral, na met\u00e1stase, na reincid\u00eancia e na resist\u00eancia ao trato. Neste estudo, os autores revisaram um estudo comparativo de melanomas cut\u00e2neos e mucocut\u00e2neos em humanos e animais, revendo as manifesta\u00e7\u00f5es cl\u00ednicas, as bases gen\u00e9ticas e as diferentes alternativas terap\u00eauticas.<\/p>\n<p><a href=\"http:\/\/www.mdpi.com\/1422-0067\/19\/2\/394\/htm\">Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas. Int J Mol Sci. 2018 Jan 30;19(2).<\/a><\/p>\n<p style=\"text-align: center;\">Archivo<\/p>\n<p style=\"text-align: center;\"><a href=\"\/pt-pt\/web-journal\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-4197 size-medium\" src=\"https:\/\/histoweb.com\/wp-content\/uploads\/2014\/11\/logo-web-journal-300x62.jpg\" alt=\"logo web journal\" width=\"300\" height=\"62\" srcset=\"https:\/\/histoweb.com\/wp-content\/uploads\/2014\/11\/logo-web-journal-300x62.jpg 300w, https:\/\/histoweb.com\/wp-content\/uploads\/2014\/11\/logo-web-journal.jpg 600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nos seres humanos, os melanomas s\u00e3o uma das neoplasias mais agressivas que, se a incid\u00eancia de formas cut\u00e2neas apresenta variabilidade dependendo da \u00e1rea geogr\u00e1fica, os melanomas \u00favidos e mucocutanos apresentam morbidades homog\u00eaneas. Tant na melanomes melanomes cutanis relaciona-se com a radia\u00e7\u00e3o UV em els mucocutanis s&#8217;han identifica diversas anomalias gen\u00e9ticas. O melanos spontanis em gossos [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":8002,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-7520","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-web-journal-pt"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Melanoma - Histoweb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/histoweb.com\/pt-pt\/melanoma\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melanoma - Histoweb\" \/>\n<meta property=\"og:description\" content=\"Nos seres humanos, os melanomas s\u00e3o uma das neoplasias mais agressivas que, se a incid\u00eancia de formas cut\u00e2neas apresenta variabilidade dependendo da \u00e1rea geogr\u00e1fica, os melanomas \u00favidos e mucocutanos apresentam morbidades homog\u00eaneas. Tant na melanomes melanomes cutanis relaciona-se com a radia\u00e7\u00e3o UV em els mucocutanis s&#8217;han identifica diversas anomalias gen\u00e9ticas. 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